Education
Recent select publications, book chapters and books:
Follman KE, Morris ME.Effects of Renal Impairment (RI) on the Prediction of Pharmacokinetics ofOrganic Cation Drugs that are Actively Secreted in the Kidney, Drug Metab Disp,46(5): 218-231, 2018 doi: 10.1124/dmd.117.079558. PMID:29490902
Bryniarski MA,Yee BM, Jaffri I, Chaves LD, Yu JA,Guan X, Ghavam N, Yacoub R, Morris ME.Increased Megalin Expression in Early Type 2 Diabetes: Role of InsulinSignaling Pathways. Am J Physiol: Renal Physiol 2018 Jun 27. doi:10.1152/ajprenal.00210.2018. [Epub ahead of print]PMID: 29949391
GuanX, Rodriguez-Cruz V, Morris ME. Cellular Uptake of MCT1 InhibitorsAR-C155858 and AZD3965 and Their Effects on MCT-Mediated Transport of L-Lactate in Murine 4T1 Breast Tumor Cancer Cells. AAPS J. 2019 Jan 7;21(2):13. doi:10.1208/s12248-018-0279-5. PMID:30617815
Jones RS, Tu C,Zhang M, Qu J and Morris ME. Characterization and Proteomic-TranscriptomicInvestigation of Monocarboxylate Transporter 6 Knockout Mice: Evidence for aPotential Role in Glucose and Lipid metabolism. Mol Pharmacol. 2019Sep;96(3):364-376. doi: 10.1124/mol.119.116731. Epub 2019 Jul 10. PMID:31436537
An G and Morris ME. Efflux Transporters in Cancer Resistance: Molecular andFunctional Characterization of Breast Cancer Resistance Protein. In DrugEfflux pumps in cancer resistance pathways: From molecular recognition andcharacterization to possible inhibition strategies in chemotherapy, Bendayan R and Sosnik A (editors) 2019.
Morris ME and Morse BL. Membrane Drug Transporters. In 8th edition of Foye’s Principles of Medicinal Chemistry. Lemke, T, Roche VF, WilliamsD and Zito SW. (editors) Lippincott Williams and Wilkins, 2019.
You G and MorrisME (editors). Drug Transporters:Molecular Characterization and Role in Drug Disposition, Wiley Press, Second edition August 2014
Complete List of Peer-reviewed Publications.
I have a broad background in the pharmaceuticalsciences with specific expertise in membrane transporters, utilizing molecularbiology techniques, tissue and cell culture studies and in vivo animal studies.My research interests have focused on the influence of membrane transport onthe pharmacokinetics and pharmacodynamics of drugs and dietary components, anddrug transporters as therapeutic targets. As such, we have focused on a number of transportersincluding members of the SLC and ABC families. Recently, my laboratory hasfocused on transport by the endocytic proteins megalin and cubilin,that are crucial in the reabsorption of endogenous and exogenous peptides andproteins in the kidney.
1986 Merck Faculty Development Award
1990 Dr.Nuala McGann Drescher Award (State
1996 NSFPOWRE Award
2003 Fellow,American Association of Pharmaceutical Scientists
2005 Faculty in Leadership Fellow, University at Buffalo
2005 Francis Dudley Meyer Award for Breast CancerResearch, Cancer Research and Prevention Foundation
2006 Chancellor’sAward in Excellence in Research and Creative Activity, State Univ. of NY
2010 Pharmacy Leadership Society Faculty Service Award,Beta Omicron Chapter, University at Buffalo
2010 Service Award, Pharmacokinetics, Pharmacodynamics and DrugMetabolism Section, American Association of Pharmaceutical Scientists
2012 Distinguished PostdoctoralMentor Award, University at Buffalo
2013 Fellow, American Association for theAdvancement of Science
2013 Distinguished Alumni Award, University ofManitoba Faculty of Pharmacy
2014 University at Buffalo DistinguishedProfessor
2015 AAPS Innovation in Biotechnology Award
2016 Research Achievement Award,Pharmacokinetics, Pharmacodynamics and Drug Metabolism Section, AmericanAssociation of Pharmaceutical Scientists
